Biphasic antibody boosting-waning model. This model assumes that for each exposure there is a set of long-term boost, long-term boost waning, short-term boost, and short-term boost waning parameters
Usage
antibody_model_biphasic(
i,
t1,
b,
exposure_histories,
biomarker_states,
kinetics_parameters,
biomarker_map,
...
)Arguments
- i
Individual
- t1
time
- b
biomarker
- exposure_histories
An array of exposure histories across all individuals, time steps and exposure IDs
- biomarker_states
An array of biomarker states (biomarker quantities) across all individuals, time steps and biomarker IDs
- kinetics_parameters
A tibble of parameters needed for the antibody kinetics model for all biomarkers
- biomarker_map
A table specifying the relationship between exposure IDs and biomarker IDs
- ...
Additional arguments
Examples
model_pars <- reformat_biomarker_map(example_model_pars_biphasic)
tmp_pars <- list()
tmp_pars[[1]] <- draw_parameters_fixed_fx_biomarker_dep(1,1,1,1,NULL, NULL, model_pars)
antibody_model_biphasic(1,1,1,example_exposure_histories_wide, example_biomarker_states_wide,
tmp_pars, example_biomarker_map_numeric)
#> [1] 0